Two new studies published in the journal Lasers in Surgery and Medicine show the PerioLase MVP-7 from Millennium Dental Technologies selectively kills bad bacteria without harming healthy tissue.
The 1064 nm wavelength laser, which is optimized for the LANAP protocol, selectively destroys Porphyromonas gingivalis (Pg), a "keystone" pathogen that directs other gum tissue bacteria to become pathogenically active in the progressive destruction involved in moderate to severe gum disease, according to a press release.
Pg has been identified as a black pigmented species bacteria based on its visible color in lab cultures. Studies have shown Pg is destroyed in human treatments following use of a 1064 nm pulsed Nd:YAG laser. These two observations led to conjecture that Pg was also pigmented in the body (in vivo), and that the 1064 nm wavelength kills the bacteria by targeting the visible (black) pigment.
"The Black Bug Myth, Selective Photodestruction of Pigmented Pathogens" by researchers David Harris, PhD, et al., demonstrates the PerioLase MVP-7 destroys Pg bacteria regardless of the amount of visible pigmentation or complete lack of visible pigmentation in the bacteria. Periodontal bugs do not need to be black, or even visible to the human eye, to be eliminated by the PerioLase MVP-7.
The second study, "Selective Photoantisepsis, “published by Harris and Reinisch, focuses on selectively eliminating pathogens at different depths within a tissue model by analyzing the differences between the absorption of light energy by pathogens and host tissues. The study supports selective destruction of Pg and Prevotella intermedia (Pi) at depths of 3-4 mm using a 1064 nm pulsed-Nd:YAG laser.
Unlike the 1064 nm wavelength, the 810 nm diode laser requires visible pigment to destroy the bacteria. The 810 nm was also lethal to healthy tissue at an earlier stage. The model indicates no selectivity for the 2940 nm Er:YAG laser.
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Source: Millennium Dental Technologies