Root canal sealer is used along with Gutta Percha for obturation of root canals. Some root canal sealers can be complete sealers where no Gutta Percha is necessary. Endodontic sealers have varying base compositions, some may be Calcium Hydroxide, epoxide-amine resins, Barium Sulfate, Bismuth Oxychloride and Zinc Oxide. Endodontic sealers can be categorized as containing Eugenol or not containing Eugenol. The component Zinc Oxide Eugenol can be placed in the root canal cavity temporarily to reduce inflammation and sensitivity. Application of endodontic sealers can be via syringe, hand mix and premeasured capsules. Working times vary greatly between vendors, be sure to indicate your preference to the vendor.